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It was found that the oncogene MYC can recruit the GAS41/SIN3A-HDAC1 complex to promote H3K27cr, thereby mediating the transcriptional repression of cell cycle inhibitor protein p21, thus promoting colorectal cancer onset and progression [45]

Further research on human PSCs is needed to confirm the application prospects of GSH

These include mitogen-activated protein kinase and nuclear factor-B (NF-B), which lead to the expression of inflammatory cytokines, chemokines, and adhesion molecules

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